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Metastasis: Nodule Lung Parenchyma Lesion

Cancers are sorted by a combination of rarity, overall frequency of metastases, and predilection for this site.


Colorectal Adenocarcinoma Common adult
Wilms Tumor Common child most common metastatic site
Non-Small Cell Lung Carcinoma Uncommon adult bronchoalveolar metastases appear as consolidation, while classical lung cancers will just appear as nodules (or lymphangiitic spread)
Renal Cell Carcinoma Common adult most common site
Melanoma Common adult second most-common site
Prostate Adenocarcinoma Rare adult
Endometrial Cancer Common adult
Testicular Cancer Common adultchild
Esophageal Cancer Common adult most common site for distant metastases from SCC (second most common for adeno)
Hepatocellular Carcinoma Common adult most common distant site
Merkel Cell Carcinoma Common adult
Papillary Thyroid Carcinoma Common adult most common site for first distant metastasis
Medullary Thyroid Carcinoma Common adult
Adrenal Cortical Carcinoma Common adult
Cervical Cancer Uncommon adult SCC lung metastases can cavitate
Osteosarcoma Common adultchild by far the most common site.

sarcoma metastases can cause pneumothorax

Epithelial Ovarian Cancer Uncommon adult
Small Cell Lung Cancer Rare adult contralateral lung
Basal Cell Carcinoma Common adult
Mixed Mullerian Tumor of the Uterus Common adult Most common metastatic site. Also, uterine carcinosarcoma has the highest rate of pulmonary metastases among uterine malignancies
Pancreatic Adenocarcinoma Uncommon adult
Gastric Adenocarcinoma Rare adult
Rhabdomyosarcoma Common child Most common site of metastasis, with best prognosis
Transitional Cell Carcinoma of the Bladder Common adult
Gallbladder Cancer Uncommon adult
Gastrointestinal Carcinoid Uncommon adult
Cholangiocarcinoma Rare adult
Non-Hodgkin's Lymphoma Rare adultchild
Hemangiopericytoma Common adult
Neuroblastoma Rare child
Pancreatic Neuroendocrine Very Rare adult
Astrocytoma Common adult most common site of extracranial metastasis
Medulloblastoma Uncommon adultchild more common in adults
Gastrointestinal Stromal Tumor Very Rare adult
Hodgkin's Lymphoma Rare adultchild can also invade locally from the hilum or mediastinum. Most common pattern is nodules.
Dermatofibrosarcoma Protuberans Common adult
Pheochromocytoma Uncommon adult