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Metastatic Pattern of Spread of Osteosarcoma  adultchild

Introduction: Malignant sarcoma arising from osteoblasts.

Prevalence: Very Rare Metastasis Frequency: Common

Br J Cancer. 1975 Jul;32(1):87-107. PMID: 1058038

Primary Tumor:

 Characteristics Comments
Bone Blastic Typically arises in the metaphysis of long bones.

Known Metastatic Locations:

SiteFrequencyCharacteristics Comments
Lung Parenchyma CommonPneumothorax, Nodule, Ossified by far the most common site.

sarcoma metastases can cause pneumothorax
radiology image: Nodules, Some with Calcium radiology image: Masses with Ossification

Bone UncommonBlastic hematogenous metastases to the spine or pelvis are most common
radiology image: Radiographically Occult Femur Metastasis radiology image: Spine Metastases
Abdomen Uncommon
Heart Uncommon
Distant Lymph Nodes Uncommon
Liver Rare
Adrenal Glands Rare
Chest Wall Rare
Thyroid Very Rare
Brain Very Rare
Spleen Very Rare
Gallbladder Very Rare
Kidney Very Rare
Pancreas Very Rare
Skin (Cutaneous and Subcutaneous) Very Rare