Metastatic Pattern of Spread of Osteosarcoma
Introduction:
Malignant sarcoma arising from osteoblasts.
Prevalence: Very Rare Metastasis Frequency: Common
References:
Br J Cancer. 1975 Jul;32(1):87-107. PMID: 1058038
Primary Tumor:
| Characteristics | Comments | |
| Bone | Blastic | Typically arises in the metaphysis of long bones. |
Known Metastatic Locations:
| Site | Frequency | Characteristics | Comments |
| Lung Parenchyma | Common | Pneumothorax, Nodule, Ossified | by far the most common site.
sarcoma metastases can cause pneumothorax |
| Bone | Uncommon | Blastic | hematogenous metastases to the spine or pelvis are most common
|
| Abdomen | Uncommon | ||
| Heart | Uncommon | ||
| Distant Lymph Nodes | Uncommon | ||
| Liver | Rare | ||
| Adrenal Glands | Rare | ||
| Chest Wall | Rare | ||
| Thyroid | Very Rare | ||
| Brain | Very Rare | ||
| Spleen | Very Rare | ||
| Gallbladder | Very Rare | ||
| Kidney | Very Rare | ||
| Pancreas | Very Rare | ||
| Skin (Cutaneous and Subcutaneous) | Very Rare |