Metastasis: Blastic Bone Lesion
Cancers are sorted by a combination of rarity, overall frequency of metastases, and predilection for this site.
| Cancer | Frequency | Comments |
| Prostate Adenocarcinoma | Common |  most common site (90%) |
| Small Cell Lung Cancer | Common | |
| Osteosarcoma | (Primary Tumor) |  Typically arises in the metaphysis of long bones. |
| Pancreatic Neuroendocrine | Uncommon | |
| Transitional Cell Carcinoma of the Bladder | Common | |
| Osteosarcoma | Uncommon | hematogenous metastases to the spine or pelvis are most common |
| Gastrointestinal Carcinoid | Uncommon | Classically, these are blastic metastases, but a recent series showed both lytic and blastic lesions (PMID: 12571207). |
| Medulloblastoma | Common | most common site of distant metastasis |
| Hodgkin's Lymphoma | Rare | Most commonly involves the spine. Involves bone usually by direct extension. |