Welcome, guest.
Login to edit.


Metastatic Pattern of Spread of Small Cell Lung Cancer  adult

Introduction: Small cell is a high-grade neuroendocrine cancer of the lung. The majority of patients present with metastatic disease.

Prevalence: Uncommon Metastasis Frequency: Common

Acta Oncol. 1999;38(8):1011-5. PMID: 10665754

J Clin Oncol. 1987 Feb;5(2):246-54. PMID: 3027269

Primary Tumor:

 Characteristics Comments
Lung Parenchyma Central the mass is typically central and may invade the mediastinum

Known Metastatic Locations:

SiteFrequencyCharacteristics Comments
Brain Common
Liver Common
Bone CommonBlastic
Bone Marrow Common
Local Lymph Nodes Common hilar and mediastinal
Pleura CommonEffusion malignant pleural effusion
Pericardium Common
Adrenal Glands Common
Distant Lymph Nodes Common retroperitoneal nodes
Trachea Uncommon
Pancreas Uncommon
Kidney Uncommon
Lung Parenchyma RareNodule contralateral lung
Esophagus Rare
Dura (Meninges) Rare
Thyroid Rare
Ovary Very Rare
Testes Very Rare
Spleen Very Rare