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Metastasis: Spleen Lesion

Cancers are sorted by a combination of rarity, overall frequency of metastases, and predilection for this site. Change metastases list to be ungrouped by characteristic.

Unspecified Characteristics

Cancer	Frequency	Comments
Melanoma	Common
Non-Small Cell Lung Carcinoma	Rare
Colorectal Adenocarcinoma	Very Rare
Small Cell Lung Cancer	Very Rare
Epithelial Ovarian Cancer	Rare
Adrenal Cortical Carcinoma	Rare
Cervical Cancer	Very Rare
Endometrial Cancer	Very Rare
Testicular Cancer	Very Rare
Esophageal Cancer	Very Rare
Cholangiocarcinoma	Very Rare
Gallbladder Cancer	Very Rare
Osteosarcoma	Very Rare
Transitional Cell Carcinoma of the Bladder	Very Rare

Enlargement

Cancer	Frequency	Comments
Non-Hodgkin's Lymphoma	Uncommon	can be radiographically occult, manifest as enlargement of the spleen, or manifest as focal lesions

Hypoenhancing

Cancer	Frequency	Comments
Hodgkin's Lymphoma	Common	Most commonly radiographically occult, but can present with hypoattenuating nodules or as splenomegaly. Splenomegaly (especially mild) does not imply involvement, however.
Non-Hodgkin's Lymphoma	Uncommon	can be radiographically occult, manifest as enlargement of the spleen, or manifest as focal lesions

Splenomegaly

Cancer	Frequency	Comments
Hodgkin's Lymphoma	Common	Most commonly radiographically occult, but can present with hypoattenuating nodules or as splenomegaly. Splenomegaly (especially mild) does not imply involvement, however.