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Metastatic Pattern of Spread of Adrenal Cortical Carcinoma  adult

Introduction: Very uncommon cancer, originating from the adrenal cortex. The minority are productive of steroid hormones. About 20-30% have distant metastases at presentation

Prevalence: Very Rare Metastasis Frequency: Common

Cancer. 1983 Aug 15;52(4):707-11. PMID: 6861107

Surgery. 1996 Feb;119(2):161-70. PMID: 8571201

Primary Tumor:

 Characteristics Comments
Adrenal Glands adrenal cortex

Known Metastatic Locations:

SiteFrequencyCharacteristics Comments
Lung Parenchyma CommonNodule
Liver Common
radiology image: Enhancing Liver Metastases
Peritoneum Common
Pleura Common
Distant Lymph Nodes Common
Bone Common
Surrounding Tissue Common
Adrenal Glands Uncommon contralateral adrenal
Inferior Vena Cava Uncommon
Spleen Rare
Pancreas Rare
Ovary Rare
Brain Very Rare
Small Intestine Very Rare
Kidney Very Rare contralateral kidney
Skin (Cutaneous and Subcutaneous) Very Rare