Metastatic Pattern of Spread of Non-Small Cell Lung Carcinoma
40% of patients have metastatic disease at presentation.
Prevalence: Common Metastasis Frequency: Common
Ann Thorac Surg. 1996 Jul;62(1):246-50. PMID: 8678651
|Lung Parenchyma||Consolidation, Spiculated, Cavitary||BAC presents as a single or multiple consolidations (in early stages, it appears as a ground-glass opacity). SCC is more likely to cavitate.
Known Metastatic Locations:
|Adrenal Glands||Common||Note that about 2/3 of isolated adrenal masses seen at diagnosis of lung cancer are benign (Radiology. 1984 Oct;153(1):217-8. PMID: 6473783).
Adeno much more likely to metastasize to adrenals than SCC.
|Lung Parenchyma||Uncommon||Consolidation, Nodule, Lymphangiitic||bronchoalveolar metastases appear as consolidation, while classical lung cancers will just appear as nodules (or lymphangiitic spread)
|Distant Lymph Nodes||Rare||abdominal or axillary lymph nodes are rare sites for metastasis in general. However, axillary nodes are more common with SCC.
|Spinal Cord||Very Rare|