Metastatic Pattern of Spread of Gallbladder Cancer
Introduction:
Cancer arising from the epithelial wall of the gallbladder, typically adenocarcinoma. The majority of cases occur in patients with gallstones.
Prevalence: Very Rare Metastasis Frequency: Common
References:
Radiographics. 2001 Mar-Apr;21(2):295-314 PMID: 11259693
J Surg Oncol. 1985 Mar;28(3):199-206. PMID: 3974247
Arch Pathol Lab Med. 2008 Jun;132(6):931-9. PMID: 18517275
Primary Tumor:
Sorry, no description has been written for the primary tumor.
Known Metastatic Locations:
| Site | Frequency | Characteristics | Comments |
| Local Lymph Nodes | Common | ||
| Distant Lymph Nodes | Common | regional nodes |
|
| Liver | Common | most common site of hematogenous metastasis |
|
| Lung Parenchyma | Uncommon | Nodule | |
| Pancreas | Uncommon | ||
| Adrenal Glands | Rare | ||
| Peritoneum | Rare | ||
| Bone | Rare | Lytic | |
| Diaphragm | Very Rare | ||
| Kidney | Very Rare | ||
| Heart | Very Rare | ||
| Omentum | Very Rare | ||
| Colon | Very Rare | ||
| Brain | Very Rare | ||
| Pleura | Very Rare | ||
| Small Intestine | Very Rare | can locally invade duodenum |
|
| Skin (Cutaneous and Subcutaneous) | Very Rare | ||
| Spleen | Very Rare |