Metastatic Pattern of Spread of Cervical Cancer
Introduction:
Cancer of the cervix is most commonly squamous cell carcinoma, but there is a minority of adenocarcinoma as well.
Prevalence: Uncommon Metastasis Frequency: Uncommon
References:
Gynecol Oncol. 1989 Jun;33(3):340-3. PMID: 2722061
Primary Tumor:
Sorry, no description has been written for the primary tumor.
Known Metastatic Locations:
| Site | Frequency | Characteristics | Comments |
| Local Lymph Nodes | Common | retroperitoneal and para-aortic |
|
| Uterus | Common | local invasion |
|
| Vagina | Common | local invasion |
|
| Ureter | Common | ||
| Bladder | Common | local invasion |
|
| Ovary | Common | ||
| Distant Lymph Nodes | Uncommon | para-tracheal |
|
| Rectum | Uncommon | local invasion |
|
| Adrenal Glands | Uncommon | seen exclusively in adenocarcinoma |
|
| Liver | Uncommon | ||
| Lung Parenchyma | Uncommon | Cavitary, Nodule | SCC lung metastases can cavitate |
| Colon | Rare | ||
| Peritoneum | Rare | Ascites | more commonly produces ascites than frank peritoneal involvement |
| Omentum | Rare | ||
| Small Intestine | Rare | ||
| Bone | Rare | Lytic | |
| Pleura | Rare | Effusion | effusion more common than frank pleural involvement |
| Gallbladder | Very Rare | ||
| Kidney | Very Rare | ||
| Pancreas | Very Rare | ||
| Spleen | Very Rare | ||
| Stomach | Very Rare | ||
| Brain | Very Rare | ||
| Skin (Cutaneous and Subcutaneous) | Very Rare |