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Metastatic Pattern of Spread of Epithelial Ovarian Cancer  adult

Introduction: The most common type of ovarian cancer is epithelial, of which there are two histologic subtypes, serous and mucinous. Serous ovarian tumors can calcify.

Prevalence: Rare Metastasis Frequency: Common

Int J Gynecol Cancer. 2003 Mar-Apr;13(2):125-9. PMID: 12657111

Cancer. 1987 Oct 1;60(7):1561-6. PMID: 3621129

Front Biosci. 1997 Jan 1;2:g8-10. PMID: 9159259

Primary Tumor:

Sorry, no description has been written for the primary tumor.

Known Metastatic Locations:

SiteFrequencyCharacteristics Comments
Local Lymph Nodes Common para-aortic
Peritoneum CommonNodule, Ascites, Hepatic Capsular most common site of metastasis
Omentum Common
Pleura CommonEffusion
Liver Uncommon i.e. parenchymal metastases. hepatic capsular metastases (from peritoneal involvement) are much more common
Lung Parenchyma UncommonNodule
Distant Lymph Nodes UncommonCalcified will calcify if serous primary
radiology image: Calcified Axillary Lymphadenopathy
Skin (Cutaneous and Subcutaneous) Rare
Brain Rare
Pericardium Rare
Spleen Rare
Bone Very RareLytic