Metastatic Pattern of Spread of Epithelial Ovarian Cancer
Introduction:
The most common type of ovarian cancer is epithelial, of which there are two histologic subtypes, serous and mucinous. Serous ovarian tumors can calcify.
Prevalence: Rare Metastasis Frequency: Common
References:
Int J Gynecol Cancer. 2003 Mar-Apr;13(2):125-9. PMID: 12657111
Cancer. 1987 Oct 1;60(7):1561-6. PMID: 3621129
Front Biosci. 1997 Jan 1;2:g8-10. PMID: 9159259
Primary Tumor:
Sorry, no description has been written for the primary tumor.
Known Metastatic Locations:
| Site | Frequency | Characteristics | Comments |
| Local Lymph Nodes | Common | para-aortic |
|
| Peritoneum | Common | Nodule, Ascites, Hepatic Capsular | most common site of metastasis |
| Omentum | Common | ||
| Pleura | Common | Effusion | |
| Liver | Uncommon | i.e. parenchymal metastases. hepatic capsular metastases (from peritoneal involvement) are much more common |
|
| Lung Parenchyma | Uncommon | Nodule | |
| Distant Lymph Nodes | Uncommon | Calcified | will calcify if serous primary
|
| Skin (Cutaneous and Subcutaneous) | Rare | ||
| Brain | Rare | ||
| Pericardium | Rare | ||
| Spleen | Rare | ||
| Bone | Very Rare | Lytic |