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Metastatic Pattern of Spread of Colorectal Adenocarcinoma  adult

Introduction: Adenocarcinoma of the colon or rectum. After resection, about 40% of patients will have a recurrence.

Prevalence: Common Metastasis Frequency: Common

Surg Gynecol Obstet. 1992 Jan;174(1):27-32. PMID 1729745

BMC Cancer. 2009 Aug 7;9:274. PMID: 19664211

Arch Pathol Lab Med. 2008 Jun;132(6):931-9. PMID: 18517275

Primary Tumor:

Sorry, no description has been written for the primary tumor.

Known Metastatic Locations:

SiteFrequencyCharacteristics Comments
Liver CommonHypoenhancing, Ring Enhancement most common site
Lung Parenchyma CommonNodule
Peritoneum Common
Local Lymph Nodes Common colon: typically along the inferior mesenteric artery

rectal: typically retroperitoneal (esp internal iliac)

Surrounding Tissue Common rectal cancer has a higher rate of local LN or surrounding tissue recurrence
Distant Lymph Nodes Rare i.e. not intra-abdominal
Bone Rare does not occur without already having mets to liver and lung
Adrenal Glands Rare
Kidney Rare
Pancreas Rare
Omentum Rare
Bladder Rare local invasion from rectal cancer
Pleura Rare much more common in rectal cancer
Uterus Very Rare
Thyroid Very Rare
Small Intestine Very Rare
Ovary Very Rare
radiology image: Ovarian Metastases
Colon Very Rare
Prostate Very Rare local invasion from rectal cancer
Skin (Cutaneous and Subcutaneous) Very Rare
Spleen Very Rare
Bronchus Very Rare PMID: 16475029 PMID: 11259704 PMID: 11243955
radiology image: Bronchial metastasis