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Metastatic Pattern of Spread of Astrocytoma  adult

Introduction: Including glioblastoma multiforme, highly malignant tumors of glial cells within the brain. They very rarely exhibit extracranial metastases but are highly locally invasive.

Prevalence: Very Rare Metastasis Frequency: Very Rare

J Neurol Neurosurg Psychiatry. 1991 Jan;54(1):80-6. PMID: 2010766

Cancer. 1980 Jan 1;45(1):112-25. PMID: 6985826

J Clin Oncol. 2011 Oct 31. PMID: 22042941

AJNR Am J Neuroradiol. 1996 Nov-Dec;17(10):1929-31. PMID: 8933881

Primary Tumor:

 Characteristics Comments

Known Metastatic Locations:

SiteFrequencyCharacteristics Comments
Lung Parenchyma CommonNodule most common site of extracranial metastasis
Distant Lymph Nodes Common most commonly cervical
Bone CommonLytic
Liver Common
Pleura Uncommon
Bone Marrow Uncommon
Peritoneum Rare seeding via ventriculoperitoneal shunt