Metastatic Pattern of Spread of Dermatofibrosarcoma Protuberans
Introduction:
Dermatofibrosarcoma Protruberans (DFSP) is a locally aggressive soft tissue sarcoma arising within the skin. Metastases are extremely rare, though local recurrence is common. A small subset (~10%) have a high-grade sarcoma component, which appears to raise the risk of recurrence or metastasis.
Lymphatic metastases are extremely rare. The lesion does invade adjacent structures, however, and MRI may be used to evaluate extent of disease preoperatively.
Prevalence: Very Rare Metastasis Frequency: Very Rare
References:
UpToDate http://www.uptodate.com/contents/dermatofibrosarcoma-protuberans
Am J Surg Pathol. 1998;22(5):576. PMID 9591728
Primary Tumor:
| Characteristics | Comments | |
| Skin (Cutaneous and Subcutaneous) | Plaque |
Known Metastatic Locations:
| Site | Frequency | Characteristics | Comments |
| Lung Parenchyma | Common | Nodule | |
| Local Lymph Nodes | Rare |