Metastatic Pattern of Spread of Gastric Adenocarcinoma
Introduction:
Adenocarcinoma arising from the stomach. Often presents as an ulcerated mass. However, it can be of a diffuse, infiltrative type (linitis plastica appearance); tumor cells infiltrate the submucosa and can be difficult to find on biopsy.
Prevalence: Uncommon Metastasis Frequency: Common
References:
Br J Surg. 2000 Feb;87(2):236-42. PMID: 10671934
Hum Pathol. 1981 Mar;12(3):237-42. PMID: 7228019
Primary Tumor:
| Characteristics | Comments | |
| Stomach | Ulcerated, Linitis Plastica, Mass | Most commonly presents as an ulcerated mass but can present as linitis plastica |
Known Metastatic Locations:
| Site | Frequency | Characteristics | Comments |
| Local Lymph Nodes | Common | ||
| Peritoneum | Common | ||
| Liver | Uncommon | ||
| Lung Parenchyma | Rare | Nodule | |
| Bone | Rare | ||
| Distant Lymph Nodes | Rare | ||
| Ovary | Rare | Krukenburg | Metastases to the surfaces of both ovaries |