Metastatic Pattern of Spread of Pheochromocytoma
Introduction:
Also known as extra-adrenal paraganglioma. It is classically stated that 10% of pheochromocytomas are malignant (have metastases). Extra-adrenal lesions are more likely to be malignant.
Prevalence: Very Rare Metastasis Frequency: Rare
References:
American Journal of Roentgenology. 2005;184:860-867 PMID: 15728610
Eur J Clin Invest. 2011 October; 41(10): 1121–1128. PMID: 21692797
Primary Tumor:
Characteristics | Comments | |
Adrenal Glands | Hyperenhancing, Cystic, T2 Hyperintense | Lesions may be partially or completely cystic (or solid). |
Known Metastatic Locations:
Site | Frequency | Characteristics | Comments |
Local Lymph Nodes | Common | ||
Liver | Common | Hyperenhancing | |
Bone | Common | ||
Lung Parenchyma | Uncommon | Nodule |