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Metastatic Pattern of Spread of Medullary Thyroid Carcinoma  adult

Introduction: Very rare thyroid cancer, often associated with MEN 2A or MEN 2B, although there are also non-MEN familial forms.

Prevalence: Very Rare Metastasis Frequency: Common

Endocrine Abstracts (2011) 26 P54

AJR Am J Roentgenol. 1982 Jul;139(1):149-55. PMID: 7046403

Primary Tumor:

 Characteristics Comments
Thyroid Calcified

Known Metastatic Locations:

SiteFrequencyCharacteristics Comments
Bone CommonLytic, Mixed Lytic and Blastic, Calcified predominantly lytic. mixed and blastic lesions have been described, however.
radiology image: Calcified and Sclerotic Metastases radiology image: Calcified and Sclerotic Vertebral Metastasis
Lung Parenchyma CommonNodule
Liver CommonCalcified
radiology image: Calcified Liver Metastases
Local Lymph Nodes Common
Mediastinum Uncommon
Brain Very Rare
Skin (Cutaneous and Subcutaneous) Very Rare
Pancreas Very Rare
Breast Very Rare
Peritoneum Very Rare
Adrenal Glands Very Rare