Metastatic Pattern of Spread of Medullary Thyroid Carcinoma
Introduction:
Very rare thyroid cancer, often associated with MEN 2A or MEN 2B, although there are also non-MEN familial forms.
Prevalence: Very Rare Metastasis Frequency: Common
References:
Endocrine Abstracts (2011) 26 P54 http://www.endocrine-abstracts.org/ea/0026/ea0026p54.htm
AJR Am J Roentgenol. 1982 Jul;139(1):149-55. PMID: 7046403
Primary Tumor:
| Characteristics | Comments | |
| Thyroid | Calcified |
Known Metastatic Locations:
| Site | Frequency | Characteristics | Comments |
| Bone | Common | Lytic, Mixed Lytic and Blastic, Calcified | predominantly lytic. mixed and blastic lesions have been described, however.
|
| Lung Parenchyma | Common | Nodule | |
| Liver | Common | Calcified |
|
| Local Lymph Nodes | Common | ||
| Mediastinum | Uncommon | ||
| Brain | Very Rare | ||
| Skin (Cutaneous and Subcutaneous) | Very Rare | ||
| Pancreas | Very Rare | ||
| Breast | Very Rare | ||
| Peritoneum | Very Rare | ||
| Adrenal Glands | Very Rare |