Metastasis: Mixed Lytic and Blastic Bone Lesion
Cancers are sorted by a combination of rarity, overall frequency of metastases, and predilection for this site.
| Cancer | Frequency | Comments |
| Breast Adenocarcinoma | Common |  less common with triple-negative cancers |
| Medullary Thyroid Carcinoma | Common | predominantly lytic. mixed and blastic lesions have been described, however. |
| Pancreatic Neuroendocrine | Uncommon | |
| Transitional Cell Carcinoma of the Bladder | Common | |
| Hodgkin's Lymphoma | Rare |  Most commonly involves the spine. Involves bone usually by direct extension. |
| Non-Hodgkin's Lymphoma | Very Rare | |