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Show Metastases by Characteristic

Metastasis: Liver Lesion

Cancers are sorted by a combination of rarity, overall frequency of metastases, and predilection for this site. Group metastases by characteristic.

 

CancerFrequencyComments
Colorectal Adenocarcinoma Common adult most common site
Breast Adenocarcinoma Common adult slightly more common in HER2-positive cancers
Non-Small Cell Lung Carcinoma Common adult
Hepatocellular Carcinoma (Primary Tumor) adult HCC lesions are arterially enhancing (versus normal liver or regenerating nodules, which enhance with the portal venous phase). The display wash-out, i.e. decreased enhancement compared to liver on PV phase.
Small Cell Lung Cancer Common adult
Wilms Tumor Uncommon child
Rhabdomyosarcoma Unspecified child Uncommon site of metastasis, frequency unspecified
Pancreatic Adenocarcinoma Common adult
Prostate Adenocarcinoma Rare adult
Melanoma Common adult
Renal Cell Carcinoma Uncommon adult
Endometrial Cancer Common adult
Testicular Cancer Common adultchild
Hepatocellular Carcinoma Common adult
Esophageal Cancer Common adult most common site for distant metastases of adenocarcinoma (second most common for SCC)
Gastric Adenocarcinoma Uncommon adult
Pancreatic Neuroendocrine Common adult overall, a very common site for metastasis (seen in about half of all pancreatic neuroendocrine tumors). However it is almost never seen from insulinomas and uncommon in VIPoma and gastrinoma.
Medullary Thyroid Carcinoma Common adult
Adrenal Cortical Carcinoma Common adult
Gastrointestinal Stromal Tumor Common adult
Cervical Cancer Uncommon adult
Epithelial Ovarian Cancer Uncommon adult i.e. parenchymal metastases. hepatic capsular metastases (from peritoneal involvement) are much more common
Cholangiocarcinoma Common adult the tumor spreads along bile ducts and vascular channels
Gallbladder Cancer Common adult most common site of hematogenous metastasis
Neuroblastoma Common child liver metastases are rare in traditional neuroblastoma, but hepatomegaly is a characteristic of "4S" disease - patient < 1 year, skin lesions ("blueberry baby"), and hepatomegaly
Basal Cell Carcinoma Common adult
Gastrointestinal Carcinoid Common adult most common distant site. Metastases will be hyperenhancing in the arterial phase, although they may become isointense to liver on later phases.
Transitional Cell Carcinoma of the Bladder Common adult
Squamous Cell Carcinoma of the Head and Neck Rare adult
Osteosarcoma Rare adultchild
Hodgkin's Lymphoma Uncommon adultchild Never occurs without splenic involvement first. Imaging is unreliable (hepatomegaly does not imply involvement).
Non-Hodgkin's Lymphoma Rare adultchild
Pheochromocytoma Common adult
Thymoma Rare adult
Papillary Thyroid Carcinoma Very Rare adult
Medulloblastoma Uncommon adultchild more common in children
Astrocytoma Common adult