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Metastasis: Arterially Enhancing Liver Lesion

Cancers are sorted by a combination of rarity, overall frequency of metastases, and predilection for this site.


Hepatocellular Carcinoma (Primary Tumor) adult HCC lesions are arterially enhancing (versus normal liver or regenerating nodules, which enhance with the portal venous phase). The display wash-out, i.e. decreased enhancement compared to liver on PV phase.
Hepatocellular Carcinoma Common adult
Renal Cell Carcinoma Uncommon adult
Pancreatic Neuroendocrine Common adult overall, a very common site for metastasis (seen in about half of all pancreatic neuroendocrine tumors). However it is almost never seen from insulinomas and uncommon in VIPoma and gastrinoma.
Gastrointestinal Carcinoid Common adult most common distant site. Metastases will be hyperenhancing in the arterial phase, although they may become isointense to liver on later phases.