Metastasis: Submucosal Small Intestine Lesion
Cancers are sorted by a combination of rarity, overall frequency of metastases, and predilection for this site.
| Cancer | Frequency | Comments |
| Gastrointestinal Carcinoid | (Primary Tumor) |  The small intestine is the most common site for GI carcinoids. The appendix used to be the most common site but is a rare site in the most recent series. The second most common site is rectum, followed by colon and stomach.
The primary tumor can be single or multiple in the small intestine. It is often overshadowed by mesenteric lymphadenopathy in size (and occasionally is not found at all). It often projects into the lumen and can cause intussusception. |
| Melanoma | Common | |